Blar i Norwegian Institute of Public Health Open Repository på forfatter "Zegeye, Ephrem Debebe"
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Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, carol; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tone, T (Peer reviewed; Journal article, 2019)Multiple regulatory mechanisms including post-translational modifications (PTMs) confer complexity to the simpler genomes and proteomes of Mycobacterium tuberculosis (Mtb). PTMs such as glycosylation play a significant ... -
Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tonjum, Tone (Peer reviewed; Journal article, 2019) -
Comparative proteomic analysis of Mycobacterium tuberculosis lineage 7 and lineage 4 strains reveals differentially abundant proteins linked to slow growth and virulence
Yimer, Solomon Abebe; Birhanu, Alemayehu Godana; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Beyene, Getachew Tesfaye; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence.
Yimer, Solomon Abebe; Godana, Alemahehu; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Tesfaye Gebeye, Getachew; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
Yimer, Solomon Abebe; Namouchi, Amine; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Meseret Tsige; Aseffa, Abraham; Tonjum, Tone (Journal article, 2016) -
Development of an enterotoxigenic Escherichia coli vaccine based on the heat-stable toxin
Zegeye, Ephrem Debebe; Govasli Larsen, Morten Andreas; Sommerfelt, Halvor; Puntervoll, Pål (Peer reviewed; Journal article, 2018)Infection with enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea-related illness and death among children under 5 years of age in low– and middle-income countries (LMIC). Recent studies have found ... -
Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli
Pradhan, Brajabandhu; Liedtke, Janine; Sleutel, Mike; Lindbäck, Toril; Zegeye, Ephrem Debebe; O_Sullivan, Kristin; Llarena, Ann-Katrin; Brynildsrud, Ola Brønstad; Aspholm, Marina Elisabeth; Remaut, Han (Peer reviewed; Journal article, 2021)Bacillus cereus sensu lato is a group of Gram-positive endospore-forming bacteria with high ecological diversity. Their endospores are decorated with micrometer-long appendages of unknown identity and function. Here, we ... -
Immunizations with enterotoxigenic Escherichia coli heat-stable toxin conjugates engender toxin-neutralizing antibodies in mice that also cross-react with guanylin and uroguanylin
Diaz, Yuleima; Govasli Larsen, Morten Andreas; Zegeye, Ephrem Debebe; Sommerfelt, Halvor; Steinsland, Hans; Puntervoll, Pål (Peer reviewed; Journal article, 2019)Infection with enterotoxigenic Escherichia coli (ETEC) is a common cause of childhood diarrhea in low- and middle-income countries, as well as of diarrhea among travelers to these countries. In children, ETEC strains ... -
Lineage-specific proteomic signatures in the Mycobacterium tuberculosis complex reveal differential abundance of proteins involved in virulence, DNA repair, CRISPR-Cas, bioenergetics and lipid metabolism
Yimer, Solomon Abebe; Kalayou, Shewit; Homberset, Håvard; Birhanu, Alemayehu Godana; Riaz, Tahira; Zegeye, Ephrem Debebe; Lutter, Timo; Abebe, Markos; Holm-Hansen, Carol; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2020)