Blar i Norwegian Institute of Public Health Open Repository på forfatter "Zimmer, Karin Elisabeth"
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Exposure to a human relevant mixture of persistent organic pollutants or to perfluorooctane sulfonic acid alone dysregulates the developing cerebellum of chicken embryo
Yadav, Ajay; Verhaegen, Steven; Filis, Panagiotis; Domanska, Diana; Lyle, Robert; Sundaram, Arvind; Leithaug, Magnus; Østby, Gunn Charlotte; Aleksandersen, Mona; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Fowler, Paul A.; Paulsen, Ragnhild Elisabeth Heimtun; Ropstad, Erik (Peer reviewed; Journal article, 2022)Prenatal exposure to persistent organic pollutants (POPs) is associated with neurodevelopmental disorders. In the present study, we explored whether a human-relevant POP mixture affects the development of chicken embryo ... -
Exposure to persistent organic pollutants alters the serum metabolome in non-obese diabetic mice
Sinioja, Tim; Bodin, Johanna Eva; Duberg, Daniel; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2022)Introduction Autoimmune disorders such as type 1 diabetes (T1D) are believed to be caused by the interplay between several genetic and environmental factors. Elucidation of the role of environmental factors in metabolic ... -
Maternal exposure to a human based mixture of persistent organic pollutants (POPs) affect gene expression related to brain function in mice offspring hippocampus
Myhre, Oddvar; Zimmer, Karin Elisabeth; Hudecova, Alexandra Misci; Hansen, Kristine Eraker Aasland; Khezri, Abdolrahman; Berntsen, Hanne Friis; Berg, Vidar; Lyche, Jan Ludvig; Mandal, Siddhartha; Duale, Nur; Ropstad, Erik (Peer reviewed; Journal article, 2021)Male and female mice pups were exposed to a low and high dose of a human relevant mixture of persistent organic pollutants (POPs) during pregnancy and lactation. Most compounds detected in the dams were found in offspring ... -
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure
Yadav, Ajay; Verhaegen, Steven; Hadera, Mussie Ghezu; Berntsen, Hanne Friis; Berg, Vidar; Lyche, Jan Ludvig; Sabaredzovic, Azemira; Haug, Line Småstuen; Myhre, Oddvar; Zimmer, Karin Elisabeth; Paulsen, Ragnhild Elisabeth; Ropstad, Erik; Boix, Fernando (Peer reviewed; Journal article, 2021) -
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes
McGlinchey, Aidan; Sinioja, Tim; Lamichhane, Santosh; Sen, Partho; Bodin, Johanna Eva; Siljander, Heli; Dickens, Alex M.; Geng, Dawei; Carlsson, Cecilia; Duberg, Daniel; Ilonen, Jorma; Virtanen, Suvi M.; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Knip, Mikael; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2020)In the last decade, increasing incidence of type 1 diabetes (T1D) stabilized in Finland, a phenomenon that coincides with tighter regulation of perfluoroalkyl substances (PFAS). Here, we quantified PFAS to examine their ...