Browsing Norwegian Institute of Public Health Open Repository by Author "Aseffa, Abraham"
Now showing items 1-15 of 15
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Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, carol; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tone, T (Peer reviewed; Journal article, 2019)Multiple regulatory mechanisms including post-translational modifications (PTMs) confer complexity to the simpler genomes and proteomes of Mycobacterium tuberculosis (Mtb). PTMs such as glycosylation play a significant ... -
Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tonjum, Tone (Peer reviewed; Journal article, 2019) -
Comparative proteomic analysis of Mycobacterium tuberculosis lineage 7 and lineage 4 strains reveals differentially abundant proteins linked to slow growth and virulence
Yimer, Solomon Abebe; Birhanu, Alemayehu Godana; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Beyene, Getachew Tesfaye; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence.
Yimer, Solomon Abebe; Godana, Alemahehu; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Tesfaye Gebeye, Getachew; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
Yimer, Solomon Abebe; Namouchi, Amine; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Meseret Tsige; Aseffa, Abraham; Tonjum, Tone (Journal article, 2016) -
High prevalence of humoral and cellular immunity to influenza viruses in pre-school children living in Addis Ababa, Ethiopia
Dembinski, Jennifer Lynn; Mihret, Adane; Yimer, Solomon Abebe; Tessema, Bamlak; Trieu, Mai Chi; Tarekegn, Azeb; Getachew, Nahom; Cox, Rebecca Jane; Oftung, Fredrik; Haneberg, Bjørn; Aseffa, Abraham; Mjaaland, Siri (Peer reviewed; Journal article, 2017) -
Lineage-specific proteomic signatures in the Mycobacterium tuberculosis complex reveal differential abundance of proteins involved in virulence, DNA repair, CRISPR-Cas, bioenergetics and lipid metabolism
Yimer, Solomon Abebe; Kalayou, Shewit; Homberset, Håvard; Birhanu, Alemayehu Godana; Riaz, Tahira; Zegeye, Ephrem Debebe; Lutter, Timo; Abebe, Markos; Holm-Hansen, Carol; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2020) -
Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia
Mihret, Wude; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Siebke, Anne-Marie; Norheim, Gunnstein; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Ayele, Samuel; Silamsaw, Mezgebu; Yamuah, Lawrence; Aseffa, Abraham; Petros, Beyene; Caugant, Dominique A; Brandtzaeg, Petter (Peer reviewed; Journal article, 2019) -
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 strains: Proteins Involved in Bioenergetics, Virulence and Antimicrobial Resistance are Acetylated
Birhanu, Alemayehu Godana; Solomon, Abebe Yimer; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markose; Tonjum, Tone (Peer reviewed; Journal article, 2017)Increasing evidence demonstrates that lysine acetylation is involved in Mycobacterium tuberculosis (Mtb) virulence and pathogenesis. However, previous investigations in Mtb have only monitored acetylation at lysine residues ... -
Prevalence and epidemiology of meningococcal carriage in Southern Ethiopia prior to implementation of MenAfriVac, a conjugate vaccine
Bårnes, Guro Kristine; Kristiansen, Paul Arne; Beyene, Demissew; Workalemahu, Bereket; Fissiha, Paulos; Merdekios, Behailu; Bohlin, Jon; Preziosi, Marie-Pierre; Aseffa, Abraham; Caugant, Dominique A (Peer reviewed; Journal article, 2016) -
Salivary and serum antibody response against Neisseria meningitidis after vaccination with conjugate polysaccharide vaccines in Ethiopian volunteers
Bårnes, Guro Kristine; Workalemahu, Bereket; Kristiansen, Paul Arne; Beyene, Demissew Balcha; Merdekios, Behailu; Fissiha, P.; Aseffa, Abraham; Caugant, Dominique A; Næss, Lisbeth Meyer (Peer reviewed; Journal article, 2016) -
Seroprevalence and risk factors of Hepatitis E Virus infection among pregnant women in Addis Ababa, Ethiopia
Abebe, Meseret; Ali, Ibrahim; Ayele, Samuel; Øverbø, Joakim; Aseffa, Abraham; Mihret, Adane (Peer reviewed; Journal article, 2017) -
Surveillance of bacterial meningitis, Ethiopia, 2012–2013
Mihret, Wude; Lema, Tsehaynesh; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Moges, Beyene; Tenna, Admasu; Woldegebriel, Fitsum; Yidnekachew, Melaku; Mekonnen, Wondale; Yamuah, Lawrence; Ahmed, Arslan; Silamsaw, Mezgebu; Petros, Beyene; Oksnes, Jan; Rosenqvist, Einar; Ayele, Samuel; Caugant, Dominique A; Aseffa, Abraham; Norheim, Gunnstein (Peer reviewed; Journal article, 2016)Ethiopia has the second-largest population (≈94 million in 2013) among the meningitis belt countries of sub-Saharan Africa (1). However, during 2001–2010, a median of only 1,056 suspected meningitis cases per year (range ... -
Vitamin D Deficiency is Associated with Increased Use of Antimicrobials among Preschool Girls in Ethiopia
Bodin, Johanna Eva; Mihret, Adane; Holm-Hansen, Carol J C; Dembinski, Jennifer Lynn; Trieu, Mai Chi; Tessema, Bamlak; Tarekegne, Azeb; Yimer, Solomon Abebe; Cox, Rebecca Jane; Aseffa, Abraham; Haneberg, Bjørn; Mjaaland, Siri (Peer reviewed; Journal article, 2019) -
Whole genome sequencing reveals within-host genetic changes in paired meningococcal carriage isolates from Ethiopia
Bårnes, Guro Kristine; Brynildsrud, Ola Brønstad; Børud, Bente; Workalemahu, Bereket; Kristiansen, Paul Arne; Beyene, Demissew; Aseffa, Abraham; Caugant, Dominique A (Peer reviewed; Journal article, 2017)