Browsing Norwegian Institute of Public Health Open Repository by Author "Johansson, Peter"
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Improved cardiovascular health by supplementation with selenium and coenzyme Q10: applying structural equation modelling (SEM) to clinical outcomes and biomarkers to explore underlying mechanisms in a prospective randomized double-blind placebo-controlled intervention project in Sweden
Alehagen, Urban; Johansson, Peter; Svensson, Erland; Aaseth, Jan; Alexander, Jan (Peer reviewed; Journal article, 2022)Purpose Selenium and coenzyme Q10 have synergistic antioxidant functions. In a four-year supplemental trial in elderly Swedes with a low selenium status, we found improved cardiac function, less cardiac wall tension and ... -
Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens
Alehagen, Urban; Johansson, Peter; Aaseth, Jan; Alexander, Jan; Brismar, Kerstin (Peer reviewed; Journal article, 2017) -
Relationship of device measured physical activity type and posture with cardiometabolic health markers: pooled dose–response associations from the Prospective Physical Activity, Sitting and Sleep Consortium
Ahmadi, Matthew N.; Blodgett, Joanna M.; Atkin, Andrew J; Chan, Hsiu-Wen; del Pozo Cruz, Borja; Suorsa, Kristin; Bakker, Esmée A.; Pulsford, Richard M.; Mielke, Gregore I; Johansson, Peter; Hettiarachchi, Pasan; Thijssen, Dick H.J.; Stenholm, Sari; Mishra, Gita D; Teixeira-Pinto, Armando; Rangul, Vegar; Sherar, Lauren B; Ekelund, Ulf; Hughes, Alun D; Lee, I-Min; Holtermann, Andreas; Koster, Annemarie; Hamer, Mark; Stamatakis, Emmanuel (Peer reviewed; Journal article, 2024)Aims/hypothesis: The aim of this study was to examine the dose–response associations of device-measured physical activity types and postures (sitting and standing time) with cardiometabolic health. Methods: We conducted ... -
Significant changes in circulating microRNA by dietary supplementation of selenium and coenzyme Q10 in healthy elderly males. A subgroup analysis of a prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens.
Alehagen, Urban; Johansson, Peter; Aaseth, Jan; Alexander, Jan; Wågsäter, Dick (Peer reviewed; Journal article, 2017)Background Selenium and coenzyme Q10 is essential for important cellular functions. A low selenium intake is reported from many European countries, and the endogenous coenzyme Q10 production is decreasing in the body with ... -
Significant changes in metabolic profiles after intervention with selenium and coenzyme q10 in an elderly population
Alehagen, Urban; Johansson, Peter; Aaseth, Jan; Alexander, Jan; Surowiec, Izabella; Lundstedt-Enkel, Katrin; Lundstedt, Torbjörn (Peer reviewed; Journal article, 2019) -
Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized double-blind placebo-controlled trial in elderly
Alehagen, Urban; Aaseth, Jan; Alexander, Jan; Johansson, Peter (Peer reviewed; Journal article, 2018)Selenium and coenzyme Q10 are both necessary for optimal cell function in the body. The intake of selenium is low in Europe, and the endogenous production of coenzyme Q10 decreases as age increases. Therefore, an intervention ... -
Supplemental selenium and coenzyme Q10 reduce glycation along with cardiovascular mortality in an elderly population with low selenium status – A four-year, prospective, randomised, double-blind placebo-controlled trial
Alehagen, Urban; Aaseth, Jan Olav; Alexander, Jan; Johansson, Peter; Larsson, Anders (Peer reviewed; Journal article, 2020)Background:A low intake of selenium has been shown to increase the risk of cardiovascular mortality, andsupplementation of selenium and coenzyme Q10 influences this. The mechanism behind is unclear althougheffects on ...