Blar i Norwegian Institute of Public Health Open Repository på forfatter "Norheim, Gunnstein"

Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex

Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, carol; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tone, T (Peer reviewed; Journal article, 2019)

Multiple regulatory mechanisms including post-translational modifications (PTMs) confer complexity to the simpler genomes and proteomes of Mycobacterium tuberculosis (Mtb). PTMs such as glycosylation play a significant ...

Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex

Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tonjum, Tone (Peer reviewed; Journal article, 2019)

An OMV Vaccine Derived from a Capsular Group B Meningococcus with Constitutive FetA Expression: Preclinical Evaluation of Immunogenicity and Toxicity

Norheim, Gunnstein; Sanders, Holly; Mellesdal, Jardar Wollan; Sundfør, Idunn (Journal article, 2015)

Association between population prevalence of smoking and incidence of meningococcal disease in Norway, Sweden, Denmark and the Netherlands between 1975 and 2009: A population-based time series analysis

Norheim, Gunnstein; Sadarangani, M; Omar, O; Yu, L-M; Molbak, K; Howitz, M; Olcen, P; Haglund, M; Van, Der, Ende, A; Pollard, AJ (Journal article, 2014)

Comparative proteomic analysis of Mycobacterium tuberculosis lineage 7 and lineage 4 strains reveals differentially abundant proteins linked to slow growth and virulence

Yimer, Solomon Abebe; Birhanu, Alemayehu Godana; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Beyene, Getachew Tesfaye; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)

In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ...

Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence.

Yimer, Solomon Abebe; Godana, Alemahehu; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Tesfaye Gebeye, Getachew; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)

In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ...

Covid-19-rekonvalesensplasma fra norske blodgivere

Nissen-Meyer, Lise Sofie Haug; Hervig, Tor Audun; Fevang, Børre; Norheim, Gunnstein; Kran, Anne-Marte Bakken; Vaage, John T.; Flesland, Øystein (Others, 2022)

Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7

Yimer, Solomon Abebe; Namouchi, Amine; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Meseret Tsige; Aseffa, Abraham; Tonjum, Tone (Journal article, 2016)

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ca Suffit!)

Henao-Restrepo, Ana Maria; Camacho, Anton; Longini, Ira M; Watle, Sara Sofie Viksmoen; Norheim, Gunnstein; Røttingen, John-Arne; Watson, Conall H.; Edmunds, W John; Matthias, Egger; W Caroll, Miles; Dean, Natalie E; Ibrahima, Diatta; Doumbia, Moussa; Draguez, Bertrand; Duraffour, Sophie; Enwere, Godwin; Grais, Rebecca; Gunther, Stephan; Gsell, Pierre-Stéphane; Hossmann, Stefanie; Konde, Mandy Kader; Keita, Sakoba; Kone, Souleymane; Kuisma, Eeva; Levine, Myron M.; Mandal, Sema; Mauget, Thomas; Riveros, Ximena; Soumah, Aboubacar; Trelle, Sven; Vicari, Andrea S.; Kieny, Marie-Paule (Peer reviewed; Journal article, 2016)

Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

Eldholm, Vegard; Norheim, Gunnstein; von der Lippe, Bent; Kinander, Wibeke; Dahle, Ulf R; Caugant, Dominique A; Mannsåker, Turid; MENGSHOEL, ANNE TORUNN; Dyrhol-Riise, Anne Ma; balloux, francois (Journal article, 2014)

Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

Eldholm, Vegard; Norheim, Gunnstein; Lippe, Bent von der; Kinander, Wibeke; Dahle, Ulf R; Caugant, Dominique A; Mannsåker, Turid; MENGSHOEL, ANNE TORUNN; Dyrhol-Riise, Anne Ma; Balloux, Francois (Journal article, 2014)

FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression

Sanders, Holly; Norheim, Gunnstein; Chan, Hannah; Dold, Christina; Vipond, Caroline; Derrick, Jeremy P; Pollard, Andrew J; Maiden, Martin C J; Feavers, Ian M (Journal article, 2015)

Genome-based transmission modelling separates imported tuberculosis from recent transmission within an immigrant population

Ayabina, Diepreye; Rønning, Janne Oseberg; Alfsnes, Kristian; Debech, Nadia; Brynildsrud, Ola Brønstad; Arnesen, Trude Margrete; Norheim, Gunnstein; Mengshoel, Anne Torunn; Rykkvin, Rikard; Dahle, Ulf R; Colijn, Caroline; Eldholm, Vegard (Peer reviewed; Journal article, 2018)

Human B Cell Responses to Dominant and Subdominant Antigens Induced by a Meningococcal Outer Membrane Vesicle Vaccine in a Phase I Trial

Rollier, Christine S.; Dold, Christina; Marsay, Leanne; Linder, Aline; Green, Christopher A.; Sadarangani, Manish; Norheim, Gunnstein; Derrick, Jeremy P.; Feavers, Ian M.; Maiden, Martin C.J.; Pollard, Andrew J. (Peer reviewed; Journal article, 2022)

Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia

Mihret, Wude; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Siebke, Anne-Marie; Norheim, Gunnstein; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Ayele, Samuel; Silamsaw, Mezgebu; Yamuah, Lawrence; Aseffa, Abraham; Petros, Beyene; Caugant, Dominique A; Brandtzaeg, Petter (Peer reviewed; Journal article, 2019)

Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 strains: Proteins Involved in Bioenergetics, Virulence and Antimicrobial Resistance are Acetylated

Birhanu, Alemayehu Godana; Solomon, Abebe Yimer; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markose; Tonjum, Tone (Peer reviewed; Journal article, 2017)

Increasing evidence demonstrates that lysine acetylation is involved in Mycobacterium tuberculosis (Mtb) virulence and pathogenesis. However, previous investigations in Mtb have only monitored acetylation at lysine residues ...

Surveillance of bacterial meningitis, Ethiopia, 2012–2013

Mihret, Wude; Lema, Tsehaynesh; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Moges, Beyene; Tenna, Admasu; Woldegebriel, Fitsum; Yidnekachew, Melaku; Mekonnen, Wondale; Yamuah, Lawrence; Ahmed, Arslan; Silamsaw, Mezgebu; Petros, Beyene; Oksnes, Jan; Rosenqvist, Einar; Ayele, Samuel; Caugant, Dominique A; Aseffa, Abraham; Norheim, Gunnstein (Peer reviewed; Journal article, 2016)

Ethiopia has the second-largest population (≈94 million in 2013) among the meningitis belt countries of sub-Saharan Africa (1). However, during 2001–2010, a median of only 1,056 suspected meningitis cases per year (range ...