Browsing Norwegian Institute of Public Health Open Repository by Author "Paulsen, Ragnhild Elisabeth Heimtun"

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Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure

Lauvås, Anna Jacobsen; Lislien, Malene; Holme, Jørn Andreas; Dirven, Hubert; Paulsen, Ragnhild Elisabeth Heimtun; Alm, Inger Margit; Andersen, Jill Mari; Skarpen, Ellen; Sørensen, Vigdis; Macko, Peter; Pistollato, Francesca; Duale, Nur; Myhre, Oddvar (Peer reviewed; Journal article, 2022)

Neural stem cells (NSCs) derived from human induced pluripotent stem cells were used to investigate effects of exposure to the food contaminant acrylamide (AA) and its main metabolite glycidamide (GA) on key neurodevelopmental ...
Exposure to a human relevant mixture of persistent organic pollutants or to perfluorooctane sulfonic acid alone dysregulates the developing cerebellum of chicken embryo

Yadav, Ajay; Verhaegen, Steven; Filis, Panagiotis; Domanska, Diana; Lyle, Robert; Sundaram, Arvind; Leithaug, Magnus; Østby, Gunn Charlotte; Aleksandersen, Mona; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Fowler, Paul A.; Paulsen, Ragnhild Elisabeth Heimtun; Ropstad, Erik (Peer reviewed; Journal article, 2022)

Prenatal exposure to persistent organic pollutants (POPs) is associated with neurodevelopmental disorders. In the present study, we explored whether a human-relevant POP mixture affects the development of chicken embryo ...