Browsing Norwegian Institute of Public Health Open Repository by Author "Selbæk, Geir"
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A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ... -
Alcohol consumption and risk of dementia up to 27 years later in a large, population-based sample: the HUNT study, Norway
Langballe, Ellen Melbye; Ask, Helga; Holmen, Jostein; Stordal, Eystein; Saltvedt, Ingvild; Selbæk, Geir; Fikseaunet, Arvid; Bergh, Sverre; Nafstad, Per; Tambs, Kristian (Journal article, 2015)The relationship between alcohol consumption and dementia risk is unclear. This investigation estimates the association between alcohol consumption reported in a population-based study in the mid-1980s and the risk for ... -
Associations between unmet needs for daytime activities and company and scores on the Neuropsychiatric Inventory-Questionnaire in people with dementia: a longitudinal study
Michelet, Mona; Selbæk, Geir; Strand, Bjørn Heine; Lund, Anne; Engedal, Knut; Bieber, Anja; Gonçalves‐Pereira, Manuel; Hopper, Louise; Irving, Kate; Jelley, Hannah; Marques, Maria J.; Orrell, Martin; Portolani, Daniel M.; Sjölund, Britt-Marie; Sköldunger, Anders; Stephan, Astrid; Verhey, Frans; de Vugt, Marjolein; Wolfs, Claire; Woods, Bob; Zanetti, Orazio; Bergh, Sverre (Peer reviewed; Journal article, 2021)Objectives: To examine prospectively the association between unmet needs for daytime activities and company and behavioural and psychological symptoms of dementia. Methods: We included 451 people with mild or moderate ... -
Associations between unmet needs for daytime activities and company and scores on the Neuropsychiatric Inventory-Questionnaire in people with dementia: a longitudinal study
Michelet, Mona; Selbæk, Geir; Strand, Bjørn Heine; Lund, Anne; Engedal, Knut; Bieber, Anja; Gonçalves‐Pereira, Manuel; Hopper, Louise; Irving, Kate; Jelley, Hannah; Marques, Maria J.; Orrell, Martin; Portolani, Daniel M.; Sjölund, Britt-Marie; Sköldunger, Anders; Stephan, Astrid; Verhey, Frans; de Vugt, Marjolein; Wolfs, Claire; Woods, Bob; Zanetti, Orazio; Bergh, Sverre (Peer reviewed; Journal article, 2021)Objectives: To examine prospectively the association between unmet needs for daytime activities and company and behavioural and psychological symptoms of dementia. Methods: We included 451 people with mild or moderate ... -
Blood pressure in dementia, mild cognitive impairment, and subjective cognitive decline related to time of death
Hestad, Knut; Engedal, Knut; Selbæk, Geir; Strand, Bjørn Heine (Peer reviewed; Journal article, 2021)Objective: It is unknown whether systolic blood pressure (SBP) drop is part of the normal aging process or due to the onset of dementia for some people. SBP drop is referring to the decrease in blood pressure often seen ... -
Blood pressure trajectories over 35 years and dementia risk: A retrospective study: The HUNT study
Selbæk, Geir; Stuebs, Josephine; Engedal, Knut; Hachinski, Vladimir; Hestad, Knut; Treviño, Cathrine Selnes; Skjellegrind, Håvard; Wedatilake, Yehani; Strand, Bjørn Heine (Peer reviewed; Journal article, 2022) -
Characteristics of patients assessed for cognitive decline in primary healthcare, compared to patients assessed in specialist healthcare
Michelet, Mona; Lund, Anne; Strand, Bjørn Heine; Engedal, Knut; Selbæk, Geir; Bergh, Sverre (Peer reviewed; Journal article, 2020)Objective: The aim of this study was to describe patients assessed for cognitive decline in primary healthcare, compared to patients assessed in specialist healthcare and to examine factors associated with depression. ... -
Cohort profile: Norwegian survey of health and ageing (NORSE)
Strand, Bjørn Heine; Skirbekk, Vegard Fykse; Langballe, Ellen Melbye; Bergh, Sverre; Landmark, Brynjar Fowels; Wangensteen, Sigrid; Selbæk, Geir; Kirkevold, Øyvind (Peer reviewed; Journal article, 2021)Purpose The Norwegian Survey of Health and Ageing (NORSE) was set up to provide internationally comparable data on ageing in Norway, which includes measured intrinsic capacity and cognitive function. Participants NORSE is ... -
Cohort profile: Norwegian survey of health and ageing (NORSE)
Strand, Bjørn Heine; Skirbekk, Vegard Fykse; Langballe, Ellen Melbye; Bergh, Sverre; Landmark, Brynjar Fowels; Wangensteen, Sigrid; Selbæk, Geir; Kirkevold, Øyvind (Peer reviewed; Journal article, 2021)Purpose The Norwegian Survey of Health and Ageing (NORSE) was set up to provide internationally comparable data on ageing in Norway, which includes measured intrinsic capacity and cognitive function. Participants NORSE is ... -
Cohort profile: the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) - a national research and quality registry with a biomaterial collection
Medbøen, Ingrid Tøndel; Persson, Karin Ester Torun; Nåvik, Marit; Totland, Torunn Holm; Bergh, Sverre; Treviño, Cathrine Selnes; Ulstein, Ingun; Engedal, Knut; Knapskog, Anne Brita; Brækhus, Anne; Øksengård, Anne Rita; Horndalsveen, Peter Otto; Saltvedt, Ingvild; Lyngroth, Anne Liv; Ranhoff, Anette Hylen; Skrettingland, Dagny B; Naik, Mala; Soares, Jelena Zugic; Johnsen, Bente; Selbæk, Geir (Peer reviewed; Journal article, 2022) -
Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study
Gjøra, Linda; Strand, Bjørn Heine; Bergh, Sverre; Borza, Tom; Brækhus, Anne; Engedal, Knut Arne; Johannessen, Aud; Kvello-Alme, Marte; Krokstad, Steinar; Livingston, Gill; Matthews, Fiona E; Myrstad, Christian; Skjellegrind, Håvard; Thingstad, Pernille; Aakhus, Eivind; Aam, Stina; Selbæk, Geir (Peer reviewed; Journal article, 2021) -
Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study
Gjøra, Linda; Strand, Bjørn Heine; Bergh, Sverre; Borza, Tom; Brækhus, Anne; Engedal, Knut Arne; Johannessen, Aud; Kvello-Alme, Marte; Krokstad, Steinar; Livingston, Gill; Matthews, Fiona E; Myrstad, Christian; Skjellegrind, Håvard; Thingstad, Pernille; Aakhus, Eivind; Aam, Stina; Selbæk, Geir (Peer reviewed; Journal article, 2021)Background: Having accurate, up-to-date information on the epidemiology of mild cognitive impairment (MCI) and dementia is imperative. Objective: To determine the prevalence of MCI and dementia in Norway using data from a ... -
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
DeMichele-Sweet, Mary Ann A.; Klei, Lambertus; Creese, Byron; Harwood, Janet C.; Weamer, Elise A.; McClain, Lora; Sims, Rebekka; Hernández, Isabel; Moreno-Grau, Sonia; Tárraga, Lluís; Boada, Mercè; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild; Skjellegrind, Håvard; Engdahl, Bo Lars; Stordal, Eystein; Andreassen, Ole Andreas; Djurovic, Srdjan; Athanasiu, Lavinia; Seripa, Davide; Borroni, Barbara; Albani, Diego; Forloni, Gianluigi; Mecocci, Patrizia; Seretti, Alessandro; De Ronchi, Diana; Politis, Antonis; Williams, Julie; Mayeux, Richard; Foroud, Tatiana; Ruiz, Agustin; Ballard, Clive; Holmans, Peter; Lopez, Oscar L.; Kamboh, M. Ilyas; Devlin, Bernie; Sweet, Robert A. (Peer reviewed; Journal article, 2021) -
Hearing loss, hearing aid use, and subjective memory complaints: Results of the HUNT study in Norway
Moradi, Shahram; Engdahl, Bo Lars; Johannessen, Aud; Selbæk, Geir; Aarhus, Lisa; Haanes, Gro Gade (Peer reviewed; Journal article, 2023)Objective. To study the association between hearing loss severity, hearing aid use, and subjective memory complaints in a large cross-sectional study in Norway. Methods. Data were drawn from the fourth wave of the Trøndelag ... -
Insomnia and risk of dementia in a large population-based study with 11-year follow-up: The HUNT study
Selbæk-Tungevåg, Selma; Selbæk, Geir; Strand, Bjørn Heine; Myrstad, Christian; Livingston, Gill; Lydersen, Stian; Bergh, Sverre; Ernstsen, Linda (Peer reviewed; Journal article, 2023) -
Leisure-Time Physical Activity Is Associated With Reduced Risk of Dementia-Related Mortality in Adults With and Without Psychological Distress: The Cohort of Norway
Zotcheva, Ekaterina; Selbæk, Geir; Bjertness, Espen; Ernstsen, Linda; Strand, Bjørn Heine (Peer reviewed; Journal article, 2018) -
Loss-of-function variants in ABCA7 confer risk of Alzheimer’s disease
Steinberg, Stacy; Stefansson, Hreinn; Jonsson, Thorlakur; Johannsdottir, Hrefna; Ingason, Andrés; Helgason, Hannes; Sulem, Patrick; Magnusson, Olafur Th; Gudjunsson, Sigurjon A; Unnsteinsdottir, Unnur; Kong, Augustine; Helisalmi, Seppo; Soininen, Hilkka; Lah, James J; Aarsland, Dag; Fladby, Tormod; Ulstein, Ingun; Djurovic, Srdjan; Sando, Sigrid Botne; White, Linda; Knudsen, Gun Peggy; Westlye, Lars Tjelta; Selbæk, Geir; Giegling, Ina; Hampel, Harald; Hiltunen, Mikko; Levey, AIlan I.; Andreassen, Ole Andreas; Rujescu, Dan; Jonsson, Palmi V.; Bjornsson, Sigurbjorn; Snaedal, Jon; Stefánsson, Kári (Journal article, 2015)We conducted a search for rare, functional variants altering susceptibility to Alzheimer’s disease that exploited knowledge of common variants associated with the same disease. We found that loss-of-function variants in ... -
Marital Histories and Associations With Later-Life Dementia and Mild Cognitive Impairment Risk in the HUNT4 70+ Study in Norway
Skirbekk, Vegard Fykse; Bowen, Catherine E; Håberg, Asta; Jugessur, Astanand; Engdahl, Bo Lars; Bratsberg, Bernt Magne; Zotcheva, Ekaterina; Selbæk, Geir; Kohler, Hans-Peter; Weiss, Jordan; Harris, Jennifer Ruth; Tom, Sarah; Krokstad, Steinar; Stern, Yaakov; Strand, Bjørn Heine (Peer reviewed; Journal article, 2022)Objectives: Earlier studies suggest that being married in later life protects against dementia, and that being single in old age increases the risk of dementia. In this study, we examine midlife marital status trajectories ... -
Mental health and wellbeing in spouses of persons with dementia: the Nord-Trøndelag health study
Ask, Helga; Langballe, Ellen Melbye; Holmen, Jostein; Selbæk, Geir; Saltvedt, Ingvild; Tambs, Kristian (Journal article, 2014) -
Midlife Physical Activity, Psychological Distress, and Dementia Risk: The HUNT Study
Zotcheva, Ekaterina; Bergh, Sverre; Selbæk, Geir; Krokstad, Steinar; Håberg, Asta; Strand, Bjørn Heine; Ernstsen, Linda (Peer reviewed; Journal article, 2018)