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dc.contributor.authorAaserud, Mortennb_NO
dc.contributor.authorLewin, Simonnb_NO
dc.contributor.authorInnvaer, Simonnb_NO
dc.contributor.authorPaulsen, Elizabeth Jnb_NO
dc.contributor.authorDahlgren, Astrid Tnb_NO
dc.contributor.authorTrommald, Marinb_NO
dc.contributor.authorDuley, Lelianb_NO
dc.contributor.authorZwarenstein, Merricknb_NO
dc.contributor.authorOxman, Andrew Davidnb_NO
dc.date.accessioned2008-10-27T09:19:54Znb_NO
dc.date.accessioned2016-02-08T14:19:34Z
dc.date.available2008-10-27T09:19:54Znb_NO
dc.date.available2016-02-08T14:19:34Z
dc.date.issued2005nb_NO
dc.identifier.citationBMC health services research 2005, 5:68en
dc.identifier.issn1472-6963nb_NO
dc.identifier.urihttp://hdl.handle.net/11250/2377828
dc.description.abstractBACKGROUND: The evidence base for improving reproductive health continues to grow. However, concerns remain that the translation of this evidence into appropriate policies is partial and slow. Little is known about the factors affecting the use of evidence by policy makers and clinicians, particularly in developing countries. The objective of this study was to examine the factors that might affect the translation of randomised controlled trial (RCT) findings into policies and practice in developing countries. METHODS: The recent publication of an important RCT on the use of magnesium sulphate to treat pre-eclampsia provided an opportunity to explore how research findings might be translated into policy. A range of research methods, including a survey, group interview and observations with RCT collaborators and a survey of WHO drug information officers, regulatory officials and obstetricians in 12 countries, were undertaken to identify barriers and facilitators to knowledge translation. RESULTS: It proved difficult to obtain reliable data regarding the availability and use of commonly used drugs in many countries. The perceived barriers to implementing RCT findings regarding the use of magnesium sulphate for pre-eclampsia include drug licensing and availability; inadequate and poorly implemented clinical guidelines; and lack of political support for policy change. However, there were significant regional and national differences in the importance of specific barriers. CONCLUSION: The policy changes needed to ensure widespread availability and use of magnesium sulphate are variable and complex. Difficulties in obtaining information on availability and use are combined with the wide range of barriers across settings, including a lack of support from policy makers. This makes it difficult to envisage any single intervention strategy that might be used to promote the uptake of research findings on magnesium sulphate into policy across the study settings. The publication of important trials may therefore not have the impacts on health care that researchers hope for.en
dc.language.isoengen
dc.publisherBioMed Centralen
dc.relation.urihttp://www.biomedcentral.com/1472-6963/5/68en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Helsetjeneste- og helseadministrasjonsforskning: 806en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.subject.meshAnticonvulsantsen
dc.subject.meshDeveloping Countriesen
dc.subject.meshDrugs, Essentialen
dc.subject.meshEvidence-Based Medicineen
dc.subject.meshFemaleen
dc.subject.meshHealth Policyen
dc.subject.meshHumansen
dc.subject.meshLegislation, Drugen
dc.subject.meshMagnesium Sulfateen
dc.subject.meshMaternal Mortalityen
dc.subject.meshObstetricsen
dc.subject.meshOrganizational Case Studiesen
dc.subject.meshPre-Eclampsiaen
dc.subject.meshPregnancyen
dc.subject.meshPrenatal Careen
dc.subject.meshRandomized Controlled Trials as Topicen
dc.titleTranslating research into policy and practice in developing countries: a case study of magnesium sulphate for pre-eclampsia.en
dc.typeJournal articleen
dc.typePeer revieweden
dc.source.journalBMC health services researchen
dc.identifier.doi10.1186/1472-6963-5-68nb_NO
dc.identifier.pmid16262902nb_NO
dc.contributor.departmentNorwegian Knowledge Centre for Health Services, Box 7004 St. Olavs Plass, N-0130 Oslo, Norway. morten.aaserud@kunnskapssenteret.noen


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