The Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019

Johansen, Tone Kristin Bjordal; Kløvstad, Hilde; Rykkvin, Rikard; Herrfurth-Erichsen, Einar Bredo; Sorthe, Joakim; Njølstad, Gro; Ebbesen, Marit Helen; Nygaard, Randi Monsen; Sandmoen, Ellen Kristin; Thilesen, Carina Merethe; Onken, Anette; Liljedal, Inger; Hadad, Ronza; Unemo, Magnus
Peer reviewed, Journal article
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http://hdl.handle.net/11250/2634050
Date
2019
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Original version
Eurosurveillance. 2019, 24 (42), .   10.2807/1560-7917.ES.2019.24.42.1900592
Abstract
The ‘Finnish new variant of Chlamydia trachomatis’ (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT variants (CT 23S rRNA C1514T and G1523A) also escaped AC2 detection. The high FI-nvCT proportion might indicate a long-term national spread and it cannot be excluded that FI-nvCT emerged in Norway.
Journal
Eurosurveillance