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dc.contributor.authorKallas, Pawel
dc.contributor.authorValen, Håkon
dc.contributor.authorHulander, Mats
dc.contributor.authorGadegaard, Nikolaj
dc.contributor.authorStormonth-Darling, John
dc.contributor.authorO'Reilly, Padraic
dc.contributor.authorThiede, Bernd
dc.contributor.authorAndersson, Martin
dc.contributor.authorHaugen, Håvard Jostein
dc.date.accessioned2022-07-27T12:24:32Z
dc.date.available2022-07-27T12:24:32Z
dc.date.created2022-04-21T10:53:44Z
dc.date.issued2022
dc.identifier.issn2040-3364
dc.identifier.urihttps://hdl.handle.net/11250/3008825
dc.description.abstractDeveloping new implant surfaces with anti-adhesion bacterial properties used for medical devices remains a challenge. Here we describe a novel study investigating nanotopography influences on bacterial adhesion on surfaces with controlled interspatial nanopillars distances. Surfaces were coated with proteins (fibrinogen, collagen, serum and saliva) prior to E. coli-WT adhesion under flow conditions. PiFM provided chemical mapping and showed that proteins adsorbed both between and onto the nanopillars with a preference to areas between the nanopillars. E. coli-WT adhered least to protein-coated areas with low surface nanopillar coverage, most to surfaces coated with saliva, while human serum led to the lowest adhesion. Protein-coated nanostructured surfaces affected the adhesion of E. coli-WT. Abstract text goes here.
dc.language.isoeng
dc.relation.urihttps://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR00976E?page=search
dc.titleProtein-coated nanostructured surfaces affect the adhesion of Escherichia coli
dc.title.alternativeProtein-coated nanostructured surfaces affect the adhesion of Escherichia coli
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionacceptedVersion
dc.description.versionsubmittedVersion
dc.source.journalNanoscale
dc.identifier.doi10.1039/D2NR00976E.
dc.identifier.cristin2018116
dc.relation.projectEU – Horisont Europa (EC/HEU): 648892
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.fulltextpreprint
cristin.qualitycode2


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