Blar i Norwegian Institute of Public Health Open Repository på forfatter "Tonjum, Tone"
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A genomic view of experimental intra- and interspecies transformation of a rifampicin resistance allele into Neisseria meningitidis
Alfsnes, Kristian; Frye, Stephan Alfons; Eriksson, JE; Tonjum, Tone; Eldholm, Vegard; Brynildsrud, Ola Brønstad; Bohlin, Jon; Harrison, OB; Hood, D; Maiden, Martin C.J.; Ambur, Ole Herman (Peer reviewed; Journal article, 2018)The spread of antibiotic resistance within and between different bacterial populations is a major health problem on a global scale. The identification of genetic transformation in genomic data from Neisseria meningitidis, ... -
Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Birhanu, Alemayehu Godana; Yimer, Solomon Abebe; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markos; Tonjum, Tone (Peer reviewed; Journal article, 2019) -
Comparative proteomic analysis of Mycobacterium tuberculosis lineage 7 and lineage 4 strains reveals differentially abundant proteins linked to slow growth and virulence
Yimer, Solomon Abebe; Birhanu, Alemayehu Godana; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Beyene, Getachew Tesfaye; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence.
Yimer, Solomon Abebe; Godana, Alemahehu; Kalayou, Shewit; Riaz, Tahira; Zegeye, Ephrem Debebe; Tesfaye Gebeye, Getachew; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Markose; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2017)In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains ofM. tuberculosis lineage 7 and lineage 4 were defined. Comparative ... -
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
Yimer, Solomon Abebe; Namouchi, Amine; Zegeye, Ephrem Debebe; Holm-Hansen, Carol J C; Norheim, Gunnstein; Abebe, Meseret Tsige; Aseffa, Abraham; Tonjum, Tone (Journal article, 2016) -
Frequency and patterns of first- and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in a cross-sectional study in Tigray Region, Ethiopia
Welekidan, Letemichael Negash; Dejene, Tsehaye Asmelash; Gebremichael, Mengistu Welday; Brynildsrud, Ola Brønstad; Tonjum, Tone; Yimer, Solomon Abebe (Peer reviewed; Journal article, 2020) -
Lineage-specific proteomic signatures in the Mycobacterium tuberculosis complex reveal differential abundance of proteins involved in virulence, DNA repair, CRISPR-Cas, bioenergetics and lipid metabolism
Yimer, Solomon Abebe; Kalayou, Shewit; Homberset, Håvard; Birhanu, Alemayehu Godana; Riaz, Tahira; Zegeye, Ephrem Debebe; Lutter, Timo; Abebe, Markos; Holm-Hansen, Carol; Aseffa, Abraham; Tonjum, Tone (Peer reviewed; Journal article, 2020) -
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 strains: Proteins Involved in Bioenergetics, Virulence and Antimicrobial Resistance are Acetylated
Birhanu, Alemayehu Godana; Solomon, Abebe Yimer; Holm-Hansen, Carol J C; Norheim, Gunnstein; Aseffa, Abraham; Abebe, Markose; Tonjum, Tone (Peer reviewed; Journal article, 2017)Increasing evidence demonstrates that lysine acetylation is involved in Mycobacterium tuberculosis (Mtb) virulence and pathogenesis. However, previous investigations in Mtb have only monitored acetylation at lysine residues ... -
Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, Ethiopia
Welekidan, Letemichael Negash; Yimer, Solomon Abebe; Skjerve, Eystein; Dejene, Tsehaye Asmelash; Homberset, Håvard; Tonjum, Tone; Brynildsrud, Ola Brønstad (Peer reviewed; Journal article, 2021)