dc.contributor.author | Kallas, Pawel | |
dc.contributor.author | Valen, Håkon | |
dc.contributor.author | Hulander, Mats | |
dc.contributor.author | Gadegaard, Nikolaj | |
dc.contributor.author | Stormonth-Darling, John | |
dc.contributor.author | O'Reilly, Padraic | |
dc.contributor.author | Thiede, Bernd | |
dc.contributor.author | Andersson, Martin | |
dc.contributor.author | Haugen, Håvard Jostein | |
dc.date.accessioned | 2022-07-27T12:24:32Z | |
dc.date.available | 2022-07-27T12:24:32Z | |
dc.date.created | 2022-04-21T10:53:44Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 2040-3364 | |
dc.identifier.uri | https://hdl.handle.net/11250/3008825 | |
dc.description.abstract | Developing new implant surfaces with anti-adhesion bacterial properties used for medical devices remains a challenge. Here we describe a novel study investigating nanotopography influences on bacterial adhesion on surfaces with controlled interspatial nanopillars distances. Surfaces were coated with proteins (fibrinogen, collagen, serum and saliva) prior to E. coli-WT adhesion under flow conditions. PiFM provided chemical mapping and showed that proteins adsorbed both between and onto the nanopillars with a preference to areas between the nanopillars. E. coli-WT adhered least to protein-coated areas with low surface nanopillar coverage, most to surfaces coated with saliva, while human serum led to the lowest adhesion. Protein-coated nanostructured surfaces affected the adhesion of E. coli-WT. Abstract text goes here. | |
dc.language.iso | eng | |
dc.relation.uri | https://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR00976E?page=search | |
dc.title | Protein-coated nanostructured surfaces affect the adhesion of Escherichia coli | |
dc.title.alternative | Protein-coated nanostructured surfaces affect the adhesion of Escherichia coli | |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.description.version | acceptedVersion | |
dc.description.version | submittedVersion | |
dc.source.journal | Nanoscale | |
dc.identifier.doi | 10.1039/D2NR00976E. | |
dc.identifier.cristin | 2018116 | |
dc.relation.project | EU – Horisont Europa (EC/HEU): 648892 | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.fulltext | preprint | |
cristin.qualitycode | 2 | |